CodonTableCodonTable

Yeast Codon Usage Table (Saccharomyces cerevisiae)

See the most used codons, highest-fraction synonymous codons, and full codon usage frequencies for Saccharomyces cerevisiae.

Use frequency to find the most common codons in this organism, and use fraction to compare synonymous codon preference within the same amino acid family.

Choose Organism and Display

These settings control the summary cards and the full codon usage table below.

Top Codons by Frequency

Codons ranked by frequency per 1,000 codons in the selected organism.
GAA
Amino acid: E
Fraction 0.71
Freq 45.9
AAA
Amino acid: K
Fraction 0.58
Freq 42.2
GAT
Amino acid: D
Fraction 0.65
Freq 37.8
AAT
Amino acid: N
Fraction 0.59
Freq 36.0
AAG
Amino acid: K
Fraction 0.42
Freq 30.8
ATT
Amino acid: I
Fraction 0.46
Freq 30.2
CAA
Amino acid: Q
Fraction 0.69
Freq 27.5
TTG
Amino acid: L
Fraction 0.29
Freq 27.1

Top Codons by Fraction

Synonymous codons ranked by fraction. Stop codons and single-codon amino acids are excluded.
GAA
Amino acid: E
Fraction 0.71
Freq 45.9
CAA
Amino acid: Q
Fraction 0.69
Freq 27.5
GAT
Amino acid: D
Fraction 0.65
Freq 37.8
CAT
Amino acid: H
Fraction 0.64
Freq 13.7
TGT
Amino acid: C
Fraction 0.63
Freq 8.0
AAT
Amino acid: N
Fraction 0.59
Freq 36.0
TTT
Amino acid: F
Fraction 0.59
Freq 26.1
AAA
Amino acid: K
Fraction 0.58
Freq 42.2

Preferred Codons by Amino Acid

One preferred codon per amino acid, ranked by frequency to surface practical defaults.
GAA
Amino acid: E
Fraction 0.71
Freq 45.9
AAA
Amino acid: K
Fraction 0.58
Freq 42.2
GAT
Amino acid: D
Fraction 0.65
Freq 37.8
AAT
Amino acid: N
Fraction 0.59
Freq 36.0
ATT
Amino acid: I
Fraction 0.46
Freq 30.2
CAA
Amino acid: Q
Fraction 0.69
Freq 27.5
TTG
Amino acid: L
Fraction 0.29
Freq 27.1
TTT
Amino acid: F
Fraction 0.59
Freq 26.1

Saccharomyces cerevisiae (Yeast): (Genetic code: Standard)

Print-friendly 2-column table in genetic code order. Frequency is shown per 1,000 codons.
TripletAmino acidFractionFrequency/ThousandNumberTripletAmino acidFractionFrequency/ThousandNumber
TTT
TTC
TTA
TTG
F
F
L
L
0.59
0.41
0.28
0.29
26.1
18.2
26.4
27.1
147,662
103,110
149,466
153,307
TCT
TCC
TCA
TCG
S
S
S
S
0.26
0.16
0.21
0.10
23.6
14.2
18.8
8.6
133,502
80,612
106,266
48,524
TAT
TAC
TAA
TAG
Y
Y
*
*
0.56
0.44
0.48
0.24
18.8
14.7
1.0
0.5
106,420
83,100
5,596
2,681
TGT
TGC
TGA
TGG
C
C
*
W
0.63
0.37
0.29
1.00
8.0
4.7
0.6
10.3
45,222
26,520
3,516
58,416
CTT
CTC
CTA
CTG
L
L
L
L
0.13
0.06
0.14
0.11
12.2
5.4
13.4
10.4
68,959
30,501
75,775
59,027
CCT
CCC
CCA
CCG
P
P
P
P
0.31
0.15
0.41
0.12
13.6
6.8
18.2
5.3
77,061
38,414
103,062
29,916
CAT
CAC
CAA
CAG
H
H
Q
Q
0.64
0.36
0.69
0.31
13.7
7.8
27.5
12.2
77,724
44,082
155,751
68,932
CGT
CGC
CGA
CGG
R
R
R
R
0.15
0.06
0.07
0.04
6.5
2.6
3.0
1.7
36,693
14,645
17,111
9,872
ATT
ATC
ATA
ATG
I
I
I
M
0.46
0.26
0.27
1.00
30.2
17.1
17.8
20.9
171,272
96,735
100,930
118,274
ACT
ACC
ACA
ACG
T
T
T
T
0.35
0.22
0.30
0.13
20.3
12.6
17.8
7.9
114,746
71,204
100,680
44,995
AAT
AAC
AAA
AAG
N
N
K
K
0.59
0.41
0.58
0.42
36.0
24.9
42.2
30.8
204,015
141,103
239,186
174,250
AGT
AGC
AGA
AGG
S
S
R
R
0.16
0.11
0.48
0.21
14.2
9.7
21.3
9.2
80,293
54,825
120,587
52,322
GTT
GTC
GTA
GTG
V
V
V
V
0.39
0.21
0.21
0.19
22.0
11.6
11.8
10.6
124,665
65,664
66,649
60,286
GCT
GCC
GCA
GCG
A
A
A
A
0.38
0.22
0.29
0.11
21.1
12.5
16.2
6.1
119,402
71,065
91,502
34,754
GAT
GAC
GAA
GAG
D
D
E
E
0.65
0.35
0.71
0.29
37.8
20.3
45.9
19.1
214,363
114,918
260,082
108,411
GGT
GGC
GGA
GGG
G
G
G
G
0.47
0.19
0.22
0.12
23.9
9.7
10.9
6.0
135,417
54,977
61,825
33,885
Showing 64 entries for Saccharomyces cerevisiae (Yeast).
Frequency is measured per 1,000 codons. Fraction compares codons that encode the same amino acid.

Common Searches

Yeast codon usage table
Yeast preferred codons
Saccharomyces cerevisiae highest fraction codons
Yeast codon bias

How To Use This Page

Use the summary cards to find the most used and highest-fraction codons quickly.
Switch sorting in the full table when you want to compare by frequency, fraction, or count.
Use the full organism list and search codons/amino acids on the Codon Usage Frequency Table.

FAQ

What are the most used codons in Saccharomyces cerevisiae?

Use the "Most Used Codons" section to see which codons appear most often in Saccharomyces cerevisiae. The ranking is based on frequency per 1,000 codons.

Which codons have the highest fraction in Saccharomyces cerevisiae?

Use the "Highest Fraction Codons" section to compare synonymous codons for the same amino acid. Single-codon amino acids and stop codons are excluded so the ranking reflects codon preference rather than trivial 1.00 values.

What is the difference between codon frequency and codon fraction in Saccharomyces cerevisiae?

Frequency measures how often a codon appears per 1,000 codons in the dataset. Fraction measures how strongly that codon is preferred relative to alternative codons encoding the same amino acid.

How should I use this Saccharomyces cerevisiae codon usage table for optimization?

Start with the preferred-codon summaries to identify likely defaults, then review the full table below before making codon optimization or expression design decisions.