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Tyrosine Amino Acid Code (Tyr, Y)
Tyrosine amino acid uses Y as its one-letter code and Tyr as its three-letter code. It is encoded by UAU, UAC.
Tyrosine Code and Properties
- Full name
- Tyrosine
- One-letter code
- Y
- Three-letter code
- Tyr
- Molecular weight
- 181.19 Da
- Essential amino acid
- No
- Charged side chain
- No
Codons for Tyrosine
What to Remember
- Y is the one-letter protein code for Tyrosine.
- Tyr is the three-letter code used in many tables, structures, and mutation notes.
- UAU, UAC are RNA codons. Coding DNA uses T where RNA uses U.
- Aromatic amino acid with a phenol group, can be phosphorylated. This page uses the standard genetic code.
Need More Context?
How to read Tyrosine in a sequence
Protein sequences usually use one-letter codes because they are compact. In that notation, Ymeans Tyrosine. The three-letter code Tyr is easier to read in structure notes, mutation descriptions, and teaching materials.
Codons are different from amino acid letter codes. A codon is a three-base RNA word read during translation, while an amino acid code is the protein shorthand. The codons UAU, UAC all point to Tyrosinein the standard genetic code.
What the property label means
The Tyrosine amino acid is classified here as aromatic. That label is a shortcut for first-pass interpretation, not a complete description of every chemical behavior.
Tyrosine is often checked because hydrophobic residues tend to be important in protein cores, membranes, and folded structural regions. The exact effect depends on protein context, neighboring residues, pH, solvent exposure, and the folded state of the whole protein.
Residue vs free amino acid
In a protein sequence, Tyrosine is usually discussed as an amino acid residue. That means the amino acid has been incorporated into a peptide chain and has lost the atoms removed during peptide bond formation. The one-letter code Y and three-letter code Tyr refer to that residue in sequence notation.
The listed molecular weight is for the free amino acid. Protein mass calculations often use residue masses instead, because water is removed when peptide bonds form.
Common mistakes
Do not confuse the one-letter code Y with a DNA or RNA base. It is an amino acid symbol, not a nucleotide in a codon.
Do not read codons without checking the frame. A triplet that encodes Tyrosine in one frame may disappear in another frame. For gene design, check organism-specific codon usage after confirming the basic amino acid identity.
Common Questions
What is the one-letter code for Tyrosine?
The one-letter amino acid code for Tyrosine is Y.
What is the three-letter code for Tyrosine?
The three-letter amino acid code for Tyrosine is Tyr.
Which codons encode Tyrosine?
Tyrosine is encoded by UAU, UAC in the standard genetic code.