Caenorhabditis elegans Codon Usage Table

See the most used codons, highest-fraction synonymous codons, and full codon usage frequencies for Caenorhabditis elegans.

Use frequency to find the most common codons in this organism, and use fraction to compare synonymous codon preference within the same amino acid family.

Escherichia coli Saccharomyces cerevisiae Arabidopsis thaliana Caenorhabditis elegans Cricetulus griseus Drosophila melanogaster Homo sapiens Spodoptera frugiperda Mus musculus Nicotiana tabacum Pichia pastoris Sus scrofa Rattus norvegicus Streptomyces Zea mays

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These settings control the summary cards and the full codon usage table below.

Top Codons by Frequency

Codons ranked by frequency per 1,000 codons in the selected organism.

GAA

Amino acid: E

Fraction 0.62

Freq 40.6

AAA

Amino acid: K

Fraction 0.59

Freq 37.9

GAT

Amino acid: D

Fraction 0.68

Freq 35.5

ATT

Amino acid: I

Fraction 0.53

Freq 32.4

GGA

Amino acid: G

Fraction 0.59

Freq 31.5

AAT

Amino acid: N

Fraction 0.62

Freq 30.3

CAA

Amino acid: Q

Fraction 0.66

Freq 27.2

AAG

Amino acid: K

Fraction 0.41

Freq 26.0

Top Codons by Fraction

Synonymous codons ranked by fraction. Stop codons and single-codon amino acids are excluded.

GAT

Amino acid: D

Fraction 0.68

Freq 35.5

CAA

Amino acid: Q

Fraction 0.66

Freq 27.2

GAA

Amino acid: E

Fraction 0.62

Freq 40.6

AAT

Amino acid: N

Fraction 0.62

Freq 30.3

CAT

Amino acid: H

Fraction 0.61

Freq 14.1

AAA

Amino acid: K

Fraction 0.59

Freq 37.9

GGA

Amino acid: G

Fraction 0.59

Freq 31.5

TAT

Amino acid: Y

Fraction 0.56

Freq 17.6

Preferred Codons by Amino Acid

One preferred codon per amino acid, ranked by frequency to surface practical defaults.

GAA

Amino acid: E

Fraction 0.62

Freq 40.6

AAA

Amino acid: K

Fraction 0.59

Freq 37.9

GAT

Amino acid: D

Fraction 0.68

Freq 35.5

ATT

Amino acid: I

Fraction 0.53

Freq 32.4

GGA

Amino acid: G

Fraction 0.59

Freq 31.5

AAT

Amino acid: N

Fraction 0.62

Freq 30.3

CAA

Amino acid: Q

Fraction 0.66

Freq 27.2

ATG

Amino acid: M

Fraction 1.00

Freq 25.9

Caenorhabditis elegans: (Genetic code: Standard)

Print-friendly 2-column table in genetic code order. Frequency is shown per 1,000 codons.

Triplet	Amino acid	Fraction	Frequency/Thousand	Number	Triplet	Amino acid	Fraction	Frequency/Thousand	Number
TTT TTC TTA TTG	F F L L	0.50 0.50 0.12 0.23	23.9 24.0 10.2 20.1	253,139 253,770 107,678 212,079	TCT TCC TCA TCG	S S S S	0.21 0.13 0.25 0.15	16.8 10.7 20.4 12.1	177,232 112,689 215,921 127,964
TAT TAC TAA TAG	Y Y * *	0.56 0.44 0.44 0.17	17.6 13.7 1.6 0.6	185,598 145,166 16,504 6,683	TGT TGC TGA TGG	C C * W	0.55 0.45 0.39 1.00	11.2 9.1 1.4 11.0	118,546 95,986 14,942 116,700
CTT CTC CTA CTG	L L L L	0.24 0.17 0.09 0.14	21.1 14.9 7.9 12.1	223,106 157,716 83,312 128,045	CCT CCC CCA CCG	P P P P	0.18 0.09 0.53 0.20	8.9 4.5 25.9 9.6	93,596 47,421 273,982 101,820
CAT CAC CAA CAG	H H Q Q	0.61 0.39 0.66 0.34	14.1 9.2 27.2 14.2	148,752 97,770 287,219 150,209	CGT CGC CGA CGG	R R R R	0.21 0.10 0.23 0.09	11.3 5.2 11.9 4.7	119,070 54,826 126,093 49,450
ATT ATC ATA ATG	I I I M	0.53 0.31 0.16 1.00	32.4 18.9 9.6 25.9	342,216 200,325 101,184 274,027	ACT ACC ACA ACG	T T T T	0.33 0.18 0.34 0.15	18.9 10.5 19.8 8.9	199,854 110,926 209,655 93,703
AAT AAC AAA AAG	N N K K	0.62 0.38 0.59 0.41	30.3 18.4 37.9 26.0	319,819 194,728 400,356 274,667	AGT AGC AGA AGG	S S R R	0.15 0.10 0.29 0.08	12.1 8.3 15.5 4.0	127,651 87,812 163,895 42,185
GTT GTC GTA GTG	V V V V	0.39 0.22 0.16 0.23	24.0 13.6 9.9 14.3	253,488 143,320 104,173 151,285	GCT GCC GCA GCG	A A A A	0.36 0.20 0.31 0.13	22.3 12.6 19.6 8.2	235,555 133,544 207,269 86,490
GAT GAC GAA GAG	D D E E	0.68 0.33 0.62 0.38	35.5 17.1 40.6 24.4	375,420 181,100 429,632 258,278	GGT GGC GGA GGG	G G G G	0.20 0.12 0.59 0.08	11.0 6.7 31.5 4.5	116,505 70,868 332,512 47,074

Showing 64 entries for Caenorhabditis elegans.

Frequency is measured per 1,000 codons. Fraction compares codons that encode the same amino acid.

Questions this table can answer

Which codons are most common in Caenorhabditis elegans?

Which synonymous codons are preferred in Caenorhabditis elegans?

Which codons should be checked before expression design?

How to use this page

Use the summary cards to find the most used and highest-fraction codons quickly.

Switch sorting in the full table when you want to compare by frequency, fraction, or count.

Use the full organism list and search codons/amino acids on the Codon Usage Frequency Table.

FAQ

What are the most used codons in Caenorhabditis elegans?

Use the "Most Used Codons" section to see which codons appear most often in Caenorhabditis elegans. The ranking is based on frequency per 1,000 codons.

Which codons have the highest fraction in Caenorhabditis elegans?

Use the "Highest Fraction Codons" section to compare synonymous codons for the same amino acid. Single-codon amino acids and stop codons are excluded so the ranking reflects codon preference rather than trivial 1.00 values.

What is the difference between codon frequency and codon fraction in Caenorhabditis elegans?

Frequency measures how often a codon appears per 1,000 codons in the dataset. Fraction measures how strongly that codon is preferred relative to alternative codons encoding the same amino acid.

How should I use this Caenorhabditis elegans codon usage table for optimization?

Start with the preferred-codon summaries to identify likely defaults, then review the full table below before making codon optimization or expression design decisions.